Papers
Book Chapters
- J. Cuesta-Barrutia, S. Hidema, H.K. Caldwell, K. Nishimori, A. Erdozain, O. Peñagarikano. (in press). In need of a specific antibody against the oxytocin receptor for neuropsychaiatric research: A KO validation study. Journal of Psychiatric Research.
- C.A. Watts, A. Haupt, J. Smith, E. Welch, A. Malik, R. Giacomino, D. Walter, N. Mavundza, H.K. Caldwell, C.M. Novak (2022). Measuring skeletal muscle thermogenesis in mice and rats. J. Vis. Exp.. July 27; (185). doi: 10.3791/64264. PMID: 35969093
- A.M. Yaw, J.D. Glass, R.A. Prosser, H.K. Caldwell (2022) Paternal cocaine in mice alters social behavior and brain oxytocin receptor density in first generation offspring. Neuroscience. Mar 1; 485:65-77.doi: 10.1016/j.neuroscience.2022.01.010. Epub 2022 Jan 19. PMID: 35063583.
- E.A. Aulino and H.K. Caldwell. (2021) Pharmacological manipulation of oxytocin receptor signaling during mouse embryonic development results in sex-specific behavioral effects in adulthood. Hormones and Behavior. Sep;135:105026. doi: 10.1016/j.yhbeh.2021.105026. Epub 2021 Jul 14.
- H.K. Caldwell. (2021) The role of oxytocin & vasopressin in the neural regulation of behavior. Oxford Research Encyclopedias. https://doi.org/10.1093/acrefore/9780190264086.013.10
- E.A. Aulino and H.K. Caldwell. (2020) Subtle sex differences in vasopressin mRNA expression in the embryonic mouse brain. Journal of Neuroendocrinology, 32(2):e12835.doi:10.1111/jne.12835.
- J.C. Morales-Medina, A. Rastogi, E. Mintz, H.K. Caldwell. (2020) Increased immediate early gene activation in the basolateral amygdala following persistent peripheral inflammation. Neuroreport, 31(10):724-729.
- K.M. Rodriguez, B.L. Smith, H.K. Caldwell. (2020) Voluntary alcohol consumption is increased in female, but not male, oxytocin receptor knockout mice. Brain Behav. 10(9):e01749.doi:10.1002/brb3.1749.
- A.R. Freeman, J.F. Hare, H.K. Caldwell. (2020) Call-specific patterns of neural activation in auditory processing of Richardson's ground squirrel alarm calls. Brain Behav. 10(6):e01629.doi:10.1002/brb3.1629.
- A.R. Freeman, E.A. Aulino, H.K. Caldwell, A.G. Ophir. (2020) Comparison of the distribution of oxytocin and vasopressin 1a receptors in rodents reveals conserved and derived patterns of nonapeptide evolution. Journal of Neuroendocrinology, 32(4):e12828.doi:10.1111/jne.12828.
- A.R. Freeman, J.F. Hare, H.K. Caldwell. (2019) Central distribution of oxytocin and vasopressin 1a receptors in juvenile Richardson's ground squirrels. Journal of Neuroscience Research, 97(7):772-789.
- H.K. Caldwell. (2018) Oxytocin and sex differences in behavior. Current Opinion in Behavioral Sciences, 23:13-20.
- A.R. Freeman, J.F. Hare, W.G. Anderson, H.K. Caldwell. (2018) Effects of arginine vasopressin on Richardson's ground squirrel social and vocal behavior. Behavioral Neuroscience, 132 (1):34-50. http://dxdoi.org/10.1037/bne0000225.
- H.K. Caldwell, E.A. Aulino, K.M. Rodriguez, S.K. Witchey, A.M. Yaw. (2017) Social context, stress, neuropsychiatric disorders, and the vasopressin 1b receptor. Front Neurosci.,11: 567. Review.
- H.K. Caldwell. (2017) Oxytocin and vasopressin: powerful regulators of social behavior. Neuroscientist, 23 (5): 517-528. Review.
- H.K. Caldwell. (2017) Who are you and where am I? New insights into how animals determine their social context. Endocrinology, 158(2):233-234. Invited Commentary.
- S.K. Witchey, E.L. Stevenson, H.K. Caldwell. (2016) Genotypic differences in intruder-evoked immediate early gene activation in male, but not female, vasopressin 1b receptor knockout mice. BMC Neurosci., 17(1):75.
- J.C. Morales-Medina, T. Iannitti, A. Freeman, H.K. Caldwell. (2016) The olfactory bulbectomized rat as a model of depression: the hippocampal pathway. Behav Brain Res., 317:562-575. Review.
- H.K. Caldwell, E.A. Aulino, A.R. Freeman, T.V. Miller, S.K. Witchey. (2016) Oxytocin and behavior: Lessons from knockout mice. Dev Neurobiol., 77(2): 190-201. Review.
- S. Tamborski, E.M. Mintz, H.K. Caldwell. (2016) Sex Differences in the embryonic development of the central oxytocin system in mice. Neuroendocrinol. 2016 Apr;28(4).
- M.E. Rich and H.K. Caldwell. (2015) A role for oxytocin in the etiology and treatment of schizophrenia. Frontiers in Endocrinology, Neuroendocrine Science: 6:90.
- T.V. Miller and H.K. Caldwell. (2015) Oxytocin during development: possible organizational effects on behavior. Frontiers in Endocrinology, Neuroendocrine Science: 6:76.
- E.L. Stevenson and H.K. Caldwell. (2014) Lesions to the CA2 region of the hippocampus impair social memory in mice. Eur J Neurosci. 40(9): 3294-301
- M.E. Rich, E.J. deCárdenas, H-J. Lee, and H.K. Caldwell. (2014) Impairments in the initiation of maternal behavior in oxytocin receptor knockout mice. PLoS ONE: 9(6): e98839.
- M.B. Dhakar, M.E. Rich, E.L. Reno, H-J. Lee, and H.K. Caldwell. (2012) Heightened aggressive behavior in mice with lifelong versus postweaning knockout of the oxytocin receptor. Hormones and Behavior, 62(1): 86-92.
- E.L. Stevenson and H.K. Caldwell. (2012) The vasopressin 1b receptor and the neural regulation of social behavior. Hormones and Behavior, 61(3): 277-282.
- A.H. Macbeth*, J.E. Stepp, H-J. Lee, W.S. Young, III, H.K. Caldwell*. (2010) Normal maternal behavior, but increased pup mortality, in conditional oxytocin receptor knockout females. Behavioral Neuroscience, 124: 677-685. (*authors contributed equally)
- H.K. Caldwell, O.E. Dike, Stevenson, E.L., K. Storck, W.S. Young, III. (2010) Social dominance in male vasopressin 1b receptor knockout mice. Hormones and Behavior, 58(2): 257-263.
- H.K. Caldwell, W. S. Young, III. (2009) Persistence of reduced aggression in vasopressin 1b receptor knockout mice on a more “wild” background. Physiology & Behavior, 97: 131
- H.K. Caldwell, S.L. Stephens, W.S. Young, III. (2009) Oxytocin as a natural antipsychotic: a study using oxytocin knockout mice. Molecular Psychiatry, 14: 190-196.
- H-J. Lee, H.K. Caldwell, A.H. Macbeth, S.G. Tolu, W.S. Young, III. (2008) A conditional knockout mouse line of the oxytocin receptor. Endocrinology, 149 (7): 3256-3263.
- H.K. Caldwell, D.A. Smith, and H.E. Albers. (2008) Photoperiodic mechanisms controlling scent marking: Interactions of vasopressin and gonadal steroids. European Journal of Neuroscience, 27: 1189-1196.
- M.L. Scattoni, H. McFarlane, V. Zhodzishsky, H.K. Caldwell, W.S. Young, L. Ricceri, J.N. Crawley. (2008) Reduced ultrasonic vocalization in vasopressin 1b knockout mice. Behavioural Brain Research, 187 (2): 371-378.
- S.R. Wersinger, J.L. Temple, H.K. Caldwell, W.S. Young, III. (2008) Inactivation of the oxytocin and the vasopressin 1b receptor genes, but not the vasopressin 1a receptor gene, impair male-induced pregnancy block. Endocrinology, 149(1): 116-121.
- H.K. Caldwell, H-J. Lee*, A.H. Macbeth*, W.S. Young, III. (2008) Vasopressin: Behavioral roles for an “original” neuropeptide. Progress in Neurobiology, 84(1): 1-24. (*authors contributed equally)
- M. Yang, M.L. Scattoni, V. Zhodzishsky, T. Chen, H.K. Caldwell, W.S. Young, H.G. McFarlane, J.N. Crawley. (2007) Similar social approach behaviors in BTBT T+ tf/J and C57BL/6J strains and vasopressin 1b receptor knockout mice tested on conventional versus reverse lighting cycles, and in replications across cohorts of vasopressin 1b mutant mice. Frontiers in Behavioral Neuroscience, 1(1):Epub.
- J.N. Crawley, T. Chen, A.Puri, T.L. Sullivan, J. M. Hill, N.B. Young, J.J. Nadler, S. Moy, L.J. Young, H.K. Caldwell, W.S. Young, III. (2007) Social approach behaviors in oxytocin knockout mice: Comparison of two independent lines tested in two laboratory environments. Neuropeptides, 41(3): 145-163.
- S.R. Wersinger, H.K. Caldwell, M. Christiansen, and W.S.Young, III. (2007) Disruption of the vasopressin 1b receptor gene impairs the attack component of social behavior in mice. Genes, Brain and Behavior, 6(7): 653-660.
- S.R. Wersinger*, H.K. Caldwell*, L. Martinez, P. Gold, Shaung-Bao, W.S. Young, III. (2007) Vasopressin 1a receptor knockout mice have a subtle olfactory deficit but normal aggression. Genes, Brain and Behavior, 6 (6): 540-551. (*authors contributed equally)
- H.K. Caldwell, J. Stewart, L. Wiedholz, R. Millstein, A. Iacangelo, A. Holmes, W.S. Young, III, and S.R. Wersinger. (2006) The acute intoxicating effects of ethanol are not dependent on the vasopressin 1a or 1b receptors. Neuropeptides, 40 (4): 325-337.
- H.K. Caldwell and H.E. Albers. (2004) Effect of photoperiod on vasopressin-induced aggression in Syrian hamsters. Hormones and Behavior, 46(4): 444-449.
- H.K. Caldwell and H.E. Albers. (2004) Photoperiodic regulation of vasopressin receptor binding in female Syrian hamsters. Brain Research, 1002: 134-139.
- H.K. Caldwell and H.E. Albers. (2003) Short-photoperiod exposure reduces vasopressin (V1a) receptor binding but not AVP-induced flank marking in male Syrian hamsters. Journal of Neuroendocrinology, 15(10): 971-977.
- H.K. Caldwell and H.E. Albers. (2002) The effects of 5-HT agonists on the hypothalamic regulation of sexual receptivity in Syrian hamsters. Hormones and Behavior 42: 78-84.
- H.K. Caldwell and J.J. Lepri. (2002) Disruption of the fifth melanocortin receptor alters the urinary excretion of aggression-modifying pheromones in male house mice. Chemical Senses, 27: 91-94.
- D.J. Fickbohm, C. Lynn-Bullock, N. Spitzer, H. Caldwell, P.Katz. (2001) Localization and quantification of 5-hydroxytryptophan and serotonin in the central nervous systems of Tritonia and Aplysia. Journal of Comparative Neurology 437: 91-105.
Book Chapters
- S.L. Veney and H.K. Caldwell (2024) Oxytocin, vasopressin, and sex differences in social behavior: It's complicated! H.K. Caldwell and H.E. Albers (eds). In "Neuroendocrinology of behavior and emotions." Springer Cham.
- H.K. Caldwell and H.E. Albers (2021) Social living and rethinking the concept of “prosociality”. W. Wilczynski and S. Brosnan (eds). In “Social Cooperation and Conflict: Biological Mechanisms at the Interface.” Cambridge University Press, Cambridge, U.K..
- H.K. Caldwell and H.E. Albers. (2016) Oxytocin, vasopressin, and the motivational forces that drive social behaviors. pp. 51-203. E. Simpson and P. Balsom (eds). In "Current Topics in Behavioral Neurosciences: Behavioral Neuroscience of Motivation". Springer.
- J.C. Morales-Medina, S.K. Witchey, and H.K. Caldwell. (2016) The role of vasopressin in anxiety and depression. In “Melatonin and Neuroprotective Agents in Neuropsychiatric Disorders” Landes Bioscience and Springer Science, Texas.
- H.K. Caldwell and H.E. Albers. (2016) Oxytocin, vasopressin, and the motivational forces that drive social behaviors. E. Simpson and P. Balsom (eds). Curr Top Behav Neurosci.;27:51-103. Springer Science, Texas.
- M.B. Dhakar*, E.L. Stevenson*, and H.K. Caldwell. (2013) Oxytocin, vasopressin and their interplay with gonadal steroids pp. 3-36. E. Choleris, D. Pfaff, and M. Kavaliers (eds). In “Oxytocin, Vasopressin and Related Peptides in the Regulation of Behavior” Cambridge University Press. (* authors contributed equally)
- H.K. Caldwell. (2012) The Neurobiology of Sociability. Pp. 187-205. Carlos Lopez-Larrea (ed). In “Sensing in Nature” Landes Bioscience and Springer Science, Texas.
- H.K. Caldwell, S.R. Wersinger, W.S. Young, III. (2008) The Role of the Vasopressin 1b Receptor in Aggression and Other Social Behaviors. Progress in Brain Research. 170: 65-72.
- H-J. Lee, H.K. Caldwell, A.H. Macbeth, W.S. Young, III. (2008) Behavioral Studies Using Temporal and Spatial Inactivation of the Oxytocin Receptor. Progress in Brain Research. 170: 73-77.
- H.K. Caldwell and W.S. Young, III. (2006) Oxytocin and Vasopressin: Genetics and Behavioral Implications, pp. 573-607. Abel Lajtha (ed). In “Handbook of Neurochemistry and Molecular Neurobiology, 3rd Edition: Volume 9: Neuroactive Proteins and Peptides (Ramon Lim (ed))” Springer, New York.
- H.K. Caldwell, L. Wang, and J.J. Lepri. (2001) Simplified tests of aggression chemosignals in male house mice suggest that a melanocortin-dependent product of the preputial gland reduces attacks, pp. 445-450. A. Marchhlewska-Koj, J. Lepri, and D. Muller-Schwarze (eds). “Chemical Signals in Vertebrates IX,” Kluwer Academic/Plenum Publishers, New York.